Latest News, Grants & Research Reports

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Research partly funded by Neuroblastoma UK leads to an innovative stem cell model providing insight into childhood cancer origins
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Research partly funded by Neuroblastoma UK leads to an innovative stem cell model providing insight into childhood cancer origins

Researchers from the University of Sheffield and St. Anna Children’s Cancer Research Institute have created a model designed to investigate the origins of neuroblastoma, a cancer primarily affecting infants and young children. The findings offer hope for the creation of tailored treatments which treat aggressive neuroblastomas and minimise the adverse effects experienced by patients from existing therapies.

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New research suggests potential combination therapy option for children with neuroblastoma to prevent resistance to treatment
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New research suggests potential combination therapy option for children with neuroblastoma to prevent resistance to treatment

New research published by Professor Suzanne Turner and led by Dr Perla Pucci in her group at the University of Cambridge Department of Pathology and CRUK Cambridge Centre Paediatric Cancer Programme, has suggested a new target for combination treatment of neuroblastoma and other cancers alongside ALK tyrosine kinase inhibitors (ALK TKI). Resistance to ALK TKI is a challenge and so additional targets for treatments that can be used in combination with ALK TKI are urgently needed.

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6th Neuroblastoma UK Research Symposium focuses on the biology of neuroblastoma, aiming for more effective and less toxic treatments for children

It was sold out two months in advance, so it was no surprise to see a packed auditorium at Selwyn College Cambridge for the 6th Neuroblastoma UK Research Symposium on 21st and 22nd March 2024. Over 130 scientists and clinicians attended from across Europe, US, and further afield, including world leading experts in pre-clinical and clinical neuroblastoma research.

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Encouraging results from the study investigating the role of Enhancer of Zeste homolog 2 (EZH2) and Natural Killer cells in Neuroblastoma

In 2023, Dr Gao, working with Prof Juliet Gray and Dr Zoë Walters at the University of Southampton, aimed to determine the role of natural killer cell- mediated anti-tumour effects in neuroblastoma, after treatment with EZH2. The objectives of the study were to look at the correlation between EZH2 protein expression and the surface expression of natural killer ligands in neuroblastoma cells, and to determine if the natural killer cells induced cytotoxicity that could be enhanced in the neuroblastoma cell lines with EZH2 inhibitors.

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Let's welcome 2024 with a hug
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Let's welcome 2024 with a hug

We know that the start of a New Year can be challenging, especially for those who have lost loved ones. At Neuroblastoma UK, we are sending our kindest thoughts to anyone struggling.  Thank you so much for your ongoing support which allows us to not only connect with you, but also to continue funding research into new, more effective and less punishing treatments for children with neuroblastoma.

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Thank you for your support in 2023
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Thank you for your support in 2023

Thank you for supporting Neuroblastoma UK in 2023.

As we draw closer to the end of a busy but exciting year, all of us at Neuroblastoma UK would like to thank you for your support in the fight against childhood cancer. Here are some of our highlights from the year.

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